PUBBLICATIONS

Papers

1.    Borner C., Bedini A., Hollt V., Kraus J., Analysis of promoter regions regulating basal and interleukin-4-inducible expression of the human CB1 receptor gene in T lymphocytes. Mol Pharmacol. 2008 Mar;73(3):1013-9. Epub 2007 Dec 21.

2.    Bedini A., Baiula M., Spampinato S., Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST. J Neurochem. 2008 Mar; 105: 2166-2178

3.    Budriesi R., Ioan P., Locatelli A., Cosconati S., Leoni A., Ugenti M.P., Andreani A., Di Toro R., Bedini A., Spampinato S., Marinelli L., Novellino E., Chiarini A., Imidazo[2,1-b]thiazole system: a scaffold endowing dihydropyridines with selective cardiodepressant activity. J Med Chem. 2008 Mar 27;51(6):1592-600. Epub 2008 Feb 28.

4.    Varoli L., Andreani A., Burnelli S., Granaiola M., Leoni A., Locatelli A., Morigi R., Rambaldi M., Bedini A, Fazio N, Spampinato S. Diphenidol-related diamines as novel muscarinic M4 receptor antagonists. Bioorg Med Chem Lett. 2008 May 1;18(9):2972-6. Epub 2008 Mar 23.

5.    Gentilucci L., Squassabia F., Demarco R., Artali R., Cardillo G., Tolomelli A., Spampinato S., Bedini A. Investigation of the interaction between the atypical agonist c[YpwFG] and MOR. FEBS J. 2008 Apr 18;275(9):2315-2337. Epub 2008 Apr 3.

6.    Borner C., Kraus J., Bedini A., Schraven B., Hollt V. T cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional {micro}-opioid receptors. Mol Pharmacol. 2008 May; 74: 496-504.

7.    Qasem AR, Bucolo C, Baiula M, Spartà A, Govoni P, Bedini A, Fascì D, Spampinato S., Contribution of alpha(4)beta(1) integrin to the antiallergic effect of levocabastine. Biochem Pharmacol. 2008 Jul; 76(6):751-62



Meetings

Poster
   
1.    Bedini A. and Spampinato S., Regulation of mu-opioid receptor by gene transcription,       32° Congresso Nazionale della Società Italiana di Farmacologia (SIF) – Napoli 1-4 Giugno 2005.

2.    F. Squassabia, L. Gentilucci, G. Cardillo, A. Tolomelli, F. Benfatti, C. Tiozzo, S. Spampinato, M. Baiula, A. Bedini, Nuovi analgesici derivati da neurotrasmettitori endogeni per il trattamento del dolore cronico in malati terminali, XIII Congresso Nazionale SICP Società Italiana di Cure Palliative -  Bologna 26-29 Aprile 2006

3.    Bedini A. and Spampinato S., Regulation of mu-opioid receptor by gene transcription,       XIX Riunione Nazionale Dottorandi in Discipline Biochimiche “A. Castellani” – Brallo di Pregola (PV) 6-9 Giugno 2006.

4.    Bedini A. and Spampinato S., PKC regulates MOR transcriptional activity: role of the proximal region of the promoter, International Narcotics Research Conference 2006 – St.Paul (Minnesota – USA) 9-14 luglio 2006

5.    Kraus J., Börner C., Bedini A. and Höllt V., Expression des Cannabinoid-Rezeptor Typ I in T-Zellen und seine Regulation durch Cannabinoide und IL-4, Deutsche Gesellschaft für experimentelle und klinische Pharmakologie und Toxikologie – 48th Spring Meeting – Mainz (Germania) 13-15 Marzo 2007.

6.    Bedini A., Di Toro R., Spampinato S., Insulin-like Growth Factor I (IGF-I) induces human mu opioid receptor (MOR) expression in differentiated neurons: role of transcription factors REST and STAT3, 33° Congresso Nazionale della Società Italiana di Farmacologia (SIF) – Cagliari 6-9 Giugno 2007

7.    Jürgen Kraus, Christine Börner, Andrea Bedini, Volker Höllt, Mechanisms of morphine-induced suppression of t cell signaling, International Narcotics Research Conference 2007 – Berlin (Germania) 8-13 Luglio 2007     

Oral Comunications

1.    Andrea Bedini, Rosanna Di Toro, Monica Baiula and Santi Spampinato, Regulation of human mu opioid receptor (hMOR) in neuronal cells and lymphocytes, XX Riunione Nazionale Dottorandi in Discipline Biochimiche “A. Castellani” – Brallo di Pregola (PV) 12-15 Giugno 2007.

2.    Andrea Bedini, Rosanna Di Toro, Monica Baiula and Santi Spampinato, Insulin-like Growth Factor I (IGF-I) modulates hMOR transcription in neuronal cells: role of STAT3, International Narcotics Research Conference 2007 – Berlin (Germania) 8-13 Luglio 2007

3.    Andrea Bedini, Monica Baiula and Santi Spampinato, PKC modulation of mu-opioid receptor gene (OPRM1) transcription is influenced by the transcription factor REST, European Opioid Conference – European Neuropeptide Club joint meeting 2008 – Ferrara (Italia) 8-11 Aprile 2008